Angebot 81 von 226 vom 15.03.2023, 14:14


Tech­ni­sche Uni­ver­si­tät Dres­den - Cen­ter for Mole­cu­lar and Cel­lu­lar Bio­en­gi­nee­ring (CMCB), Bio­tech­no­logy Cen­ter (BIO­TEC), Rese­arch Group Bio­me­di­cal Geno­mics

The Bio­tech­no­logy Cen­ter (BIO­TEC) ( and its part­ner insti­tu­ti­ons, Cen­ter for Mole­cu­lar Bio­en­gi­nee­ring (B CUBE) and the Cen­ter for Rege­ne­ra­tive The­ra­pies Dres­den (CRTD), are equip­ped with state-of-the-art faci­li­ties for Mole­cu­lar Bio­sci­ence rese­arch ( They are part of a rich and col­la­bo­ra­tive envi­ron­ment that inclu­des the Faculty of Mathe­ma­tics, the Carl Gus­tav Carus Faculty of Medi­cine, the Max-Planck- Insti­tute of Mole­cu­lar Cell Bio­logy and Gene­tics (MPI-CBG) and the Leib­niz Insti­tute for Poly­mer Rese­arch Dres­den (IPF). For TU Dres­den (TUD) diver­sity is an essen­tial fea­ture and a qua­lity cri­ter­ion of an excel­lent uni­ver­sity. Accord­in­gly, we wel­come all app­li­cants who would like to com­mit them­sel­ves, their achie­ve­ments and pro­duc­tivity to the suc­cess of the whole insti­tu­tion.

Rese­arch Asso­ciate / Post­doc Com­pu­ta­tio­nal Sin­gle Cell Omics (m/f/x)


At the Bio­tech­no­logy Cen­ter (BIO­TEC), an Insti­tute of the Cen­ter for Mole­cu­lar and Cel­lu­lar Bio­en­gi­nee­ring (CMCB), the Rese­arch Group Bio­me­di­cal Geno­mics offers a posi­tion as
Rese­arch Asso­ciate / Post­doc Com­pu­ta­tio­nal Sin­gle Cell Omics (m/f/x)
(sub­ject to per­so­nal qua­li­fi­ca­tion employees are remu­ne­ra­ted accord­ing to salary group E 13 TV-L)
star­ting June 1, 2023. The posi­tion is limi­ted to 2 years. An exten­sion to appro­xi­mately 4 years is anti­ci­pa­ted. The period of employ­ment is gover­ned by the Fixed Term Rese­arch Con­tracts Act (Wis­sen­schafts­zeit­ver­trags­ge­setz-WissZeitVG). The posi­tion offers the chance to obtain fur­ther aca­de­mic qua­li­fi­ca­tion.

Working field:

Injury in an orga­nism leads to major chan­ges in cel­lu­lar orga­ni­za­tion and alte­ra­ti­ons of gene regu­latory pro­grams. Such alte­ra­ti­ons now become visi­ble in unpre­ce­den­ted detail with sin­gle cell tech­no­lo­gies. To streng­t­hen our diverse team, we are loo­king for a post­doc­to­ral fel­low to study sin­gle cell multi-omics as part of the DFG sequen­cing pro­ject „The uni­que rege­ne­ra­tive state of spi­nal pro­ge­ni­tors“. We will inves­ti­gate sin­gle-cell beha­viour in zebra­fish in the con­text of spi­nal cord rege­ne­ra­tion using sin­gle cell omics, such as simul­ta­ne­ous sin­gle cell RNA- and ATAC-seq. Using multi-omics data inte­gra­tion and machine lear­ning, we will inves­ti­gate beha­viours and gene-regu­latory net­work chan­ges in spi­nal pro­ge­ni­tor cells in response to spi­nal cord injury. The pro­ject is a col­la­bo­ra­tion bet­ween the Chair of Neural Deve­lop­ment and Rege­ne­ra­tion (Prof. Cathe­rina Becker) and the com­pu­ta­tio­nal Rese­arch Group Bio­me­di­cal Geno­mics (Dr. Anna Poe­tsch), where this posi­tion will be based. The suc­cess­ful can­di­date will have the oppor­tu­nity to receive trai­ning in cut­ting-edge methods in multi-omics data inte­gra­tion and the pos­si­bi­lity to learn and apply machine lear­ning and deep lear­ning methods on geno­mics data.


  • excel­lent uni­ver­sity and PhD degree with expe­ri­ence in mole­cu­lar bio­logy, com­pu­ta­tio­nal bio­logy, gene­tics, geno­mics, or equi­va­lent sci­en­ti­fic back­ground with an excel­lent under­stan­ding of genome bio­logy;
  • com­pre­hen­sive pro­gramming expe­ri­ence in python and/or R;
  • demons­tra­ble expe­ri­ence in multi-omics and/or sin­gle cell omics data ana­ly­sis;
  • very good inter­per­so­nal and com­mu­ni­ca­tion skills; in par­ti­cu­lar, the abi­lity to effec­tively work in a diverse, col­la­bo­ra­tive and inter­di­sci­pli­nary rese­arch envi­ron­ment;
  • flu­ency in Eng­lish - writ­ten and oral (Ger­man is not requi­red).

What we offer:

The BIO­TEC/CMCB is a renow­ned inter­di­sci­pli­nary and inter­na­tio­nal rese­arch insti­tute of the TUD that boasts a col­la­bo­ra­tive spi­rit and cut­ting-edge tech­no­logy plat­forms, inclu­ding one of the natio­nal genome cen­tres and cut­ting-edge High Per­for­mance Com­pu­ting resour­ces. The city of Dres­den pro­vi­des nume­rous chan­ces for sci­en­ti­fic exchange and col­la­bo­ra­tion.

How to apply:

TUD stri­ves to employ more women in aca­de­mia and rese­arch. We the­re­fore expressly encou­rage women to apply. The Uni­ver­sity is a cer­ti­fied family-fri­endly uni­ver­sity and offers a Dual Career Ser­vice. We wel­come app­li­ca­ti­ons from can­di­da­tes with disa­bi­li­ties. If mul­ti­ple can­di­da­tes prove to be equally qua­li­fied, those with disa­bi­li­ties or with equi­va­lent sta­tus pur­suant to the Ger­man Social Code IX (SGB IX) will receive prio­rity for employ­ment.
Please sub­mit your com­pre­hen­sive app­li­ca­tion inclu­ding the usual docu­ments (inclu­ding a let­ter of moti­va­tion, your CV inclu­ding a list of publi­ca­ti­ons, tran­scripts of records, and con­tact details for 2-3 aca­de­mic refe­ren­ces) by April 13, 2023 (stam­ped arri­val date of the uni­ver­sity cen­tral mail ser­vice app­lies) pre­fer­a­bly via the TU Dres­den Secu­re­Mail Por­tal by sen­ding it as a sin­gle pdf docu­ment to, or to: TU Dres­den, BIO­TEC, For­schungs­gruppe Bio­me­di­zi­ni­sche Geno­mik, Frau Dr. Anna Poe­tsch, Helm­holtz­str. 10, 01069 Dres­den, Ger­many. Please sub­mit copies only, as your app­li­ca­tion will not be retur­ned to you. Expen­ses incur­red in atten­ding inter­views can­not be reim­bur­sed.

Refe­rence to data pro­tec­tion: Your data pro­tec­tion rights, the pur­pose for which your data will be pro­ces­sed, as well as fur­ther infor­ma­tion about data pro­tec­tion is avail­able to you on the web­site: